Intramuscular rolitertracycline nitrate (Tetrex PMT) in non-specific urethritis.

With an agreed success rate of about 85 per cent. the role of oral oxytetracycline hydrochloride in the treatment of non-specific urethritis was firmly established a decade ago. Other oral tetracyclines have proved of similar value. While the results obtained with intramuscular oxytetracycline and other tetracyclines have been comparable, the incidence of pain at the injection site has been such that this form of administration could not be recommended for routine use (Morton, 1961). Intramuscular medication avoids gastrointestinal side-effects, eliminates sharing of treatment with a consort, and gives proof that treatment has been taken. Rolitetracycine nitrate has advantages over former tetracyclines in that it is said to cause significantly less pain on injection, is more efficiently absorbed, and produces and maintains adequate blood levels for 24 hours after a single intramuscular injection. It was therefore proposed to conduct a trial of this preparation in the treatment of nonspecific urethritis. Each vial of Tetrex PMT contains: